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Sibutramine Tablets are one of the most popular oral substances intended for reducing body weight. Therefore, it is used in bodybuilding as well as in medicine. It creates a feeling of fullness and satiety in the body and thus causes that the body does not want to receive any more calories. Sibutramine is an inhibitor of the neurotransmitters in the brain, in the right place where the appetite and satiety are controlled. The product can lead to the loss of 10 - 15% of the original weight. The loss in weight has positive effects on the levels of blood lipids, cholesterol. While receiving sibutramine, the customer shall be on a low calorie diet.
CHEMICAL NAME: (±)-Dimethyl-1-[1-(4-chlorophenyl) cyclobutyl]-N, N, 3-trimethylbutan-1-amine
HALF RELEASE: 1 hour
Sibutramin is a centrally acting inhibitor of reducing levels of serotonin and noradrenaline. It is structurally similar to amphetamines, although the mechanism of action is different.
Sibutramine reduces the uptake of serotonin (by 53%), norepinephrine (by 54%), and dopamine (by 16%), which increases the levels of these substances in the synaptic cleft, and help to increase the feeling of satiety, and thus affect the appetite. Older anorectic agents such as amphetamine and fenfluramine caused the more an increase of the release of these neurotransmitters, than the effect on the uptake. Although the mechanism of action is similar to that of tricyclic antidepressants, sibutramine has not shown antidepressant properties in the studies.
The use of sibutramine may cause kidney problems or digestive problems. It is a very dangerous product for people with heart problems, because it can lead to irregular heartbeat and high blood pressure, which in extreme cases can cause a heart attack.The most common side effects of sibutramine are headache, nausea, constipation or insomnia.
For the purposes of fat burning and weight reduction the maximum daily dose of sibutramine is 10 mg.
|Effective in reducing body weight||the presence of frequent side effects|