Clomiphene Citrate

27,99 €
Availability
In stock
Package
50mg/tab (50 tablets)
Brand
Genesis
Category
Post Cycle Therapy (PCT)

CLOMIFENE CITRATE
CHEMICAL NAME: (E, Z) -2 (4 - (2-chloro-1,2-diphenylethenyl) phenoxy)-N, N-diethyl-ethanamine
HALF RELEASE: 5-7 days

Clomifene Citrate belongs to the category of compounds known as selective estrogen receptor modulators (SERMs).Selective estrogen receptor modulators are in a more broad class of compounds known as anti-estrogens.Other sub-group of anti-estrogen categories include aromatase inhibitors, antiestrogens (AIS) such as anastrozole, exemestane, and anastrozol.

Substances from category SERM serve to block the action of estrogen receptors in the mammary tissue.They occupy estrogen receptors in place of estrogen and estrogen alone will be unable to exercise its effects.It also operate in other tissues in the body (such as tamoxifen in the liver). Substances from category SERM don't reduce the levels of circulating estrogen in the blood plasma (aromatase inhibitors serve this purpose). Although clomifene is a very close relative of the tamoxifen, in fact it is much less efficient compared with tamoxifen.That is, it is a weaker estrogen blocker in mammary tissue where tamoxifen is much more suitable for the task.

Clomifene phenethyl acts as an estrogen antagonist in the hypothalamus, pituitary ovaries, endometrium, vagina and cervix.That is, in those tissues and body regions, Clomifene serves to reducte (or completely block the inhibition) of action of estrogens. For both men and women, its estrogen antagonistic effect on the hypothalamus triggers the release of LH (luteinizing hormone) and FSH (follicle stimulus hormone).These two hormones in men are signaling hormones on the testes, which then start producing or increasing testosterone production.

Clomifene and tamoxifen may be considered as estrogen, which acts as a "fake" estrogen in certain areas of the body, such as breast tissue.By blocking the effects of "real'' estrogen, while in other tissues is active real estrogen.

For athletes and bodybuilders who use anabolic steroids clomifene can serve as an effective anti-estrogen to relieve one particular side effect which is gynecomastia. Clomifene can be used effectively to increase the endogenous production of testosterone in men during the program for restoring the natural formation of testosterone known as PCT (Post Cycle Therapy).Traditional programs for such use is a combination of substances tamoxifen and clomifene and hCG (human chorionic gonadotropin) for several weeks.

Advantages
  • Blocks the action of estrogen
  • Causes an increase in natural testosterone production

Disadvantages
  • it is a synthetic estrogen with lower efficiency
  • less effective than tamoxifen

For the purpose of preventing or reducing the symptoms of gynecomastia during treatment a dose within the range of approximately 50 - 100 mg per day is used. In some cases, the required dose is above 100 mg.

The standard dose of Clomid in PCT program (to support the creation of natural testosterone), is also in the range 50 - 100 mg per day.

CLOMIFENE CITRATE
CHEMICAL NAME: (E, Z) -2 (4 - (2-chloro-1,2-diphenylethenyl) phenoxy)-N, N-diethyl-ethanamine
HALF RELEASE: 5-7 days

Clomifene Citrate belongs to the category of compounds known as selective estrogen receptor modulators (SERMs).Selective estrogen receptor modulators are in a more broad class of compounds known as anti-estrogens.Other sub-group of anti-estrogen categories include aromatase inhibitors, antiestrogens (AIS) such as anastrozole, exemestane, and anastrozol.

Substances from category SERM serve to block the action of estrogen receptors in the mammary tissue.They occupy estrogen receptors in place of estrogen and estrogen alone will be unable to exercise its effects.It also operate in other tissues in the body (such as tamoxifen in the liver). Substances from category SERM don't reduce the levels of circulating estrogen in the blood plasma (aromatase inhibitors serve this purpose). Although clomifene is a very close relative of the tamoxifen, in fact it is much less efficient compared with tamoxifen.That is, it is a weaker estrogen blocker in mammary tissue where tamoxifen is much more suitable for the task.

Clomifene phenethyl acts as an estrogen antagonist in the hypothalamus, pituitary ovaries, endometrium, vagina and cervix.That is, in those tissues and body regions, Clomifene serves to reducte (or completely block the inhibition) of action of estrogens. For both men and women, its estrogen antagonistic effect on the hypothalamus triggers the release of LH (luteinizing hormone) and FSH (follicle stimulus hormone).These two hormones in men are signaling hormones on the testes, which then start producing or increasing testosterone production.

Clomifene and tamoxifen may be considered as estrogen, which acts as a "fake" estrogen in certain areas of the body, such as breast tissue.By blocking the effects of "real'' estrogen, while in other tissues is active real estrogen.

For athletes and bodybuilders who use anabolic steroids clomifene can serve as an effective anti-estrogen to relieve one particular side effect which is gynecomastia. Clomifene can be used effectively to increase the endogenous production of testosterone in men during the program for restoring the natural formation of testosterone known as PCT (Post Cycle Therapy).Traditional programs for such use is a combination of substances tamoxifen and clomifene and hCG (human chorionic gonadotropin) for several weeks.

Advantages
Disadvantages
  • Blocks the action of estrogen
  • Causes an increase in natural testosterone production

  • it is a synthetic estrogen with lower efficiency
  • less effective than tamoxifen

For the purpose of preventing or reducing the symptoms of gynecomastia during treatment a dose within the range of approximately 50 - 100 mg per day is used. In some cases, the required dose is above 100 mg.

The standard dose of Clomid in PCT program (to support the creation of natural testosterone), is also in the range 50 - 100 mg per day.

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