Description

Sibutramine is an inhibitor of the neurotransmitters in the brain, in the right place where the appetite and satiety are controlled. The product can lead to the loss of 10 – 15% of the original weight. The loss in weight has positive effects on the levels of blood lipids, cholesterol. While receiving sibutramine, the customer shall be on a low calorie diet.

SIBUTRAMINE
CHEMICAL NAME:   (±)-Dimethyl-1-[1-(4-chlorophenyl) cyclobutyl]-N, N, 3-trimethylbutan-1-amine
HALF RELEASE:   1 hour

Characteristics

Sibutramin is a centrally acting inhibitor of reducing levels of serotonin and noradrenaline. It is structurally similar to amphetamines, although the mechanism of action is different.

Sibutramine reduces the uptake of serotonin (by 53%), norepinephrine (by 54%), and dopamine (by 16%), which increases the levels of these substances in the synaptic cleft, and help to increase the feeling of satiety, and thus affect the appetite.

Older anorectic agents such as amphetamine and fenfluramine caused the more an increase of the release of these neurotransmitters, than the effect on the uptake. Although the mechanism of action is similar to that of tricyclic antidepressants, sibutramine has not shown antidepressant properties in the studies.

Side Effects

Using sibutramine can cause problems such as:

• Kidney problems
• Digestive problems
• Irregular heartbeat
• High blood pressure
• In extreme cases, a heart attack
• Headache
• Nausea
• Constipation
• Insomnia

Dosage

For the purposes of fat burning and weight reduction the maximum daily dose of sibutramine is 10 mg.